Mitochondrial Bioenergetic,Photobiomodulation and Trigeminal Branches Nerve Damage,What’s the Connection? A Review

Background: Injury of the trigeminal nerve in oral and maxillofacial surgery can occur. Schwann cell mitochondria are regulators in the development, maintenance and regeneration of peripheral nerve axons. Evidence shows that after the nerve injury, mitochondrial bioenergetic dysfunction occurs and is associated with pain, neuropathy and nerve regeneration deficit. A challenge for research is to individuate new therapies able to normalise mitochondrial and energetic metabolism to aid nerve recovery after damage. Photobiomodulation therapy can be an interesting candidate, because it is a technique involving cell manipulation through the photonic energy of a non-ionising light source (visible and NIR light), which produces a nonthermal therapeutic effect on the stressed tissue. Methods: The review was based on the following questions: (1) Can photo-biomodulation by red and NIR light affect mitochondrial bioenergetics? (2) Can photobiomodulation support damage to the trigeminal nerve branches? (preclinical and clinical studies), and, if yes, (3) What is the best photobiomodulatory therapy for the recovery of the trigeminal nerve branches? The papers were searched using the PubMed, Scopus and Cochrane databases. This review followed the ARRIVE-2.0, PRISMA and Cochrane RoB-2 guidelines. Results and conclusions: The reliability of photobiomodulatory event strongly bases on biological and physical-chemical evidence. Its principal player is the mitochondrion, whether its cytochromes are directly involved as a photoacceptor or indirectly through a vibrational and energetic variation of bound water: water as the photoacceptor. The 808-nm and 100 J/cm² (0.07 W; 2.5 W/cm²; pulsed 50 Hz; 27 J per point; 80 s) on rats and 800-nm and 0.2 W/cm² (0.2 W; 12 J/cm²; 12 J per point; 60 s, CW) on humans resulted as trustworthy therapies, which could be supported by extensive studies.     

脉冲激光与电弧布置方式对铝合金焊接熔滴过渡与焊缝形貌的影响

以2219铝合金为基板，研究了不同脉冲激光-电弧布置方式下的熔滴过渡与焊缝形貌特征，分析了熔深增加的机理. 结果表明，当脉冲激光照射母材时，脉冲激光主要提供对母材的热输入，母材温度的增加有助于促进熔滴铺展，稳定熔滴过渡过程；当脉冲激光照射熔滴缩颈时，主要提供对熔滴的力输入，蒸发反力的作用下形成"一脉一滴"，显著提高熔滴过渡频率与熔滴飞行速度，增加了熔滴对熔池的冲击力，熔深增加；当脉冲激光交替的照射熔池和熔滴时，一方面能够对母材进行加热，有助于熔滴的铺展，另一方面能够提高熔滴过渡频率，提高焊缝的均匀性.     

超厚板TC4钛合金电子束焊接接头应力腐蚀敏感性

针对100 mm超厚板TC4钛合金电子束焊接接头，采用慢应变速率拉伸方法评价接头在人造海水中的应力腐蚀敏感性，分析接头的显微组织和断口形貌，对接头的腐蚀机制进行研究. 结果表明，室温条件下应变速率为ε=1×10-6 s-1时，母材在海水中未表现出应力腐蚀敏感性；焊缝上部、中部和下部具有轻微应力腐蚀敏感性. 焊缝在海水中发生阳极溶解，产生氢吸附，导致裂纹的萌生. 同时氢扩散诱导α'相界及α'相内发生位错塞积，进而使裂纹在更低的应力水平下发生扩展.     

蜂窝梁的稳定性能研究进展

对蜂窝梁破坏模式的研究表明，失稳是其结构性能失效的重要破坏模式。为此，在回顾蜂窝梁结构特性研究的基础上，总结归纳了蜂窝梁失稳的3种主要模式：整体弯扭失稳、梁墩屈曲、畸变屈曲。结合国内外近30多年来对蜂窝梁稳定性的试验研究成果，对影响蜂窝梁稳定性的主要因素进行分析。采用蒙特卡洛法得到纯弯简支蜂窝梁弯扭失稳临界荷载的概率分布和影响因子的敏感度。将部分具有代表性的试验成果与欧洲规范EN 1993-1-1计算结果进行对比，根据中国规范GB 50068—2001《建筑结构可靠度设计统一标准》提供的抗力分项系数，计算了不同荷载组合下蜂窝梁整体弯扭失稳临界荷载的可靠度指标，为国内规范的制订提供依据。最后，总结了当前蜂窝梁稳定性研究中存在的不足，指明了进一步研究的方向。     

Enhancement of optical emission generated from femtosecond double-pulse laser-induced glass plasma at different sample temperatures in air

In double-pulse laser-induced breakdown spectroscopy(DP-LIBS), the collinear femtosecond double-pulse laser configuration is experimentally investigated with different initial sample temperatures using a Ti:sapphire laser. The glass sample is ablated to produce the plasma spectroscopy. During the experiment, the detected spectral lines include two Na(I) lines(589.0 nm and 589.6 nm) and one Ca(I) line at the wavelength of 585.7 nm. The emission lines are measured at room temperature(22 ℃) and three higher initial sample temperatures(T_s?=?100 ℃, 200 ℃, and 250 ℃). The inter-pulse delay time ranges from-250 ps to 250 ps.The inter-pulse delay time and the sample temperature strongly influence the spectral intensity,and the spectral intensity can be significantly enhanced by increasing the sample temperature and selecting the optimized inter-pulse time. For the same inter-pulse time of 0 ps(single-pulse LIBS), the enhancement ratio is approximately 2.5 at T_s?=?200 ℃ compared with that obtained at T_s?=?22 ℃. For the same inter-pulse time of 150 ps, the enhancement ratio can be up to 4 at T_s?=?200 ℃ compared with that obtained at T_s?=?22 ℃. The combined enhancement effects of the different initial sample temperatures and the double-pulse configuration in femtosecond LIBS are much stronger than that of the different initial sample temperatures or the double-pulse configuration only.     

激光刻痕对取向电工钢磁畴和铁损的影响

为了研究激光刻痕工艺参数对取向电工钢表面的磁畴形貌、刻痕线宽度和铁损的影响规律，开展了激光刻痕工艺试验。结果表明，激光刻痕后取向电工钢表面的磁畴宽度明显细化，且随着输入电流的增加，磁畴宽度先减小后增大；刻痕线宽度随着输入电流的增加而增大。对于本次试验样品，通过对比分析，确定最佳激光刻痕工艺参数为电流为 12 A，激光频率为 5 kHz，刻痕速度为 800 mm/s，该参数下铁损改善率可达 11.81%。     

Improved Corrosion Resistance of Selective Laser Melted Ti–5Cu Alloy Using Atomized Ti–5Cu Powder

The different types of metal powder used for selective laser melting(SLM) process would cause distinct corrosion behavior due to the uniformity of the obtained microstructure.The SLM-produced Ti–5Cu alloy using atomized Ti–5Cu metal powder(SLMed Ti–5Cu) in this work reveals a relatively uniform microstructure with overwhelming acicular α/α′ phase and shows great advantages on corrosion resistance compared with the SLM-produced Ti–5Cu alloy using the mixture powder(SLMedM Ti–5Cu).The effect of the micro-galvanic cells decreases due to the undetectable Ti_2Cu phase in the microstructure of the SLMed Ti–5Cu.An apparent passivation behavior was observed for SLMed Ti–5Cu instead of severe pitting phenomenon for the SLMed-M Ti–5Cu.The charge transfer resistance of SLMed Ti–5Cu in this work is 10.09 ± 2.63 MΩ cm~2, which is significantly higher than that of SLMed-M Ti–5Cu(4.76 MΩ cm~2).The above result indicates the atomized Ti–5Cu powder plays an important role in the formation of the uniform microstructure of SLMed product, thereby enhancing its corrosion resistance in Hank's solution at 37 ℃.     

基于同轴图像传感的激光焊接过程质量监测技术

针对激光焊接过程中由于参数不匹配、装配误差等原因造成的焊接过程不稳定等焊接缺陷，基于同轴图像传感技术，建立起一套激光焊接过程中的质量在线监测系统，对焊接过程中的熔池图像进行了采集分析及其熔池特征信息的提取. 结果表明，在激光功率为1 500 W的不等厚不锈钢薄板激光焊接试验条件下，焊接过程中的不稳定、下塌缺陷以及焊偏现象与熔池形状各特征信息变化具有一定的相关性. 结合BP神经网络算法对所提特征信息进行分类、识别，基于LabVIEW软件平台，可实现相应缺陷的自动化识别及报警功能.     

基于飞秒激光制备的光子晶体光纤Fabry-Perot温度传感器

提出并设计了一种基于飞秒激光在光子晶体光纤(photonic crystal fiber,PCF)中制备光纤法布里-珀罗(Fabry-Perot,F-P)传感器的方法。采用飞秒脉冲激光作为加工光源,结合放大倍率100×的物镜以及三维加工平台在PCF侧面采用逐线刻写方式进行加工。通过对飞秒激光光斑在光纤上的聚焦位置以及刻写功率进行优化,在PCF上刻写了深度均为80 μm、间隔为800 μm的两条划线,实现了周期为0.98 nm的全光纤F-P结构制备；实验中,对传感器在40~120 ℃温度范围内的光谱特性进行了测试与分析,每隔10 ℃进行一次数据采集,随着温度逐渐增加波长向长波方向漂移,通过对该采样点数据进行线性拟合,得到该测试点的波长温度灵敏度为9.73 pm/℃,拟合线性度为0.997。